URS-12-EN-28-OIC ACID, 2,3,23-TRIHYDROXY-, (2A,3B,4A)-
Asiatic acid
CAS: 464-92-6
Molecular Formula: C30H48O5
URS-12-EN-28-OIC ACID, 2,3,23-TRIHYDROXY-, (2A,3B,4A)- - Names and Identifiers
URS-12-EN-28-OIC ACID, 2,3,23-TRIHYDROXY-, (2A,3B,4A)- - Physico-chemical Properties
| Molecular Formula | C30H48O5 |
| Molar Mass | 488.7 |
| Density | 1.18±0.1 g/cm3(Predicted) |
| Melting Point | 325-330°C(lit.) |
| Boling Point | 609.4±55.0 °C(Predicted) |
| Specific Rotation(α) | +53.9°（pyridine） |
| Flash Point | 336.4°C |
| Water Solubility | Soluble in dimethyl sulfoxide, ethanol and dimethylformamide. Sparingly soluble in water |
| Solubility | Soluble in methanol, DMSO, insoluble in petroleum ether, chloroform. |
| Vapor Presure | 2.13E-17mmHg at 25°C |
| Appearance | White crystal |
| Color | white |
| pKa | 4.66±0.70(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.579 |
| MDL | MFCD00238541 |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, is derived from the whole grass of Centella asiatica. |
URS-12-EN-28-OIC ACID, 2,3,23-TRIHYDROXY-, (2A,3B,4A)- - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| WGK Germany | 3 |
| RTECS | YU9580000 |
| HS Code | 29181990 |
URS-12-EN-28-OIC ACID, 2,3,23-TRIHYDROXY-, (2A,3B,4A)- - Reference
| Reference Show more | 1. Yin Yue, Zou Yong, Cheng Binbin. Effects of Asiatic acid on proliferation, migration and apoptosis of human hepatocellular carcinoma SMMC-7721 cells [J]. Chinese Medicine Guide, 2019, v.25;No.342(20):83-86. 2. Gu Shenyong, Zhu Qiuzhen, Wang Jing, et al. Protective effect of Asiatic acid on brain injury and its mechanism [J]. Journal of Pharmaceutical Practice, 2016(3):206-209. 3. Zhao, Yun, et al. "Effect of centella asiatica on oxidative stress and lipid metabolism in hyperlipid animal models." Oxidative Medicine and Cellular Longevity 2014 (2014).https://doi.org/10.1155/2014/154295 4. Jiang, Hui, et al. "Identification of Centella asiatica's effective ingredients for inducing the neuronal differentiation." Evidence-Based Complementary and Alternative Medicine 2016 (2016).https://doi.org/10.1155/2016/9634750 5. Xu, Changgeng, et al. "Asiatic acid ameliorates tubulointerstitial fibrosis in mice with ureteral obstruction." Experimental and therapeutic medicine 6.3 (2013): 731-736.https://doi.org/10.3892/etm.2013.1197 6. [IF=6.543] Zhao Yun et al."Effect of Centella asiatica on Oxidative Stress and Lipid Metabolism in Hyperlipidemic Animal Models."Oxid Med Cell Longev. 2014;2014:154295 7. [IF=1.984] Jiang Hui et al."Identification of Centella asiatica's Effective Ingredients for Inducing the Neuronal Differentiation."Evid-Based Compl Alt. 2016;2016:9634750 8. [IF=1.785] Changgeng Xu et al."Asiatic acid ameliorates tubulointerstitial fibrosis in mice with ureteral obstruction."Exp Ther Med. 2013 Sep;6(3):731-736 9. [IF=2.408] Amit Jaisi et al."Investigation of HIV-1 Viral Protein R Inhibitory Activities of Twelve Thai Medicinal Plants and Their Commercially Available Major Constituents."Chemistry & Biodiversity. 2021 Oct 27 |
URS-12-EN-28-OIC ACID, 2,3,23-TRIHYDROXY-, (2A,3B,4A)- - Reference Information
| plant source: | asiatica |
| introduction | asiatic acid (AA), also known as Asiatic acid, is one of the main components of triterpene extract of natural plant Cestella asiatica (Centella asiatica (L.) Urban), and has ursulane skeleton structure. |
| properties | milky white or white powder; The air is slight; It tastes bitter. |
| use | has anti-irritation. Skin repair, inhibit collagen synthesis; Improve keratinization function; Stimulate skin cells, etc. asiatic acid has the effects of antidepressant, anti-gastric ulcer, anti-tumor and memory enhancement. used for content determination/identification/pharmacological experiment, etc. Pharmacological effects: This product has the effects of improving depression, anti-cancer, preventing myocardial infarction, cerebral thrombosis, cerebral infarction, enhancing memory, and whitening skin. |
| effect on skin | since Chasseaud and others confirmed in 1971 that asiatic acid itself has the effect of treating skin trauma, the asiatica extract (mainly containing asiatica and asiatica saponin) has been used to treat skin trauma and chronic ulcer, as well as skin deformation caused by tuberculosis and leprosy. |
| biological activity | Asiatic acid (Dammarolic acid, Asiantic acid) is the glycoside of asiaticoside, which is isolated from the plant Cestella asiatica and is often used for wound healing. |
| Target | Value |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 20:49:11
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Product Name: Asiatic Acid Visit Supplier Webpage Request for quotationCAS: 464-92-6
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Asiatic acid Visit Supplier Webpage Request for quotationCAS: 464-92-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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